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"start": "2026-09-18", "cities": [ "Nashville" ] }, { "id": "NCT07828860", "title": "Safety and Efficacy of Soquelitinib in Adults With Hidradenitis Suppurativa", "sponsor": "Corvus Pharmaceuticals, Inc.", "phase": "PHASE1", "start": "2026-09-17", "cities": [ "Nashville" ] }, { "id": "NCT07701941", "title": "A Study of Patritumab Deruxtecan (HER3-DXd) in Combination With Trastuzumab Deruxtecan (T-DXd) in Participants With HR-Positive, HER2-Low or HER2-Ultralow Unres", "sponsor": "Daiichi Sankyo", "phase": "PHASE1/PHASE2", "start": "2026-09-17", "cities": [ "Memphis", "Nashville" ] }, { "id": "NCT07832292", "title": "A Study of JNJ-101556143 in Participants With Metastatic Prostate Cancer", "sponsor": "Janssen Research & Development, LLC", "phase": "PHASE2", "start": "2026-09-16", "cities": [ "Germantown" ] }, { "id": "NCT07817251", "title": "Research Study on How People With Type 2 Diabetes Tolerate Switching From Semaglutide to Cagrisema", "sponsor": "Novo Nordisk A/S", "phase": "PHASE3", "start": "2026-09-16", "cities": [ "Nashville" ] }, { "id": "NCT07510048", "title": "Combatting HIV Or Other STIs Early (CHOOSE)", "sponsor": "Westat", "phase": "NA", "start": "2026-09-16", "cities": [ "Memphis" ] }, { "id": "NCT07766499", "title": "A Study to Assess the Efficacy and Safety of THB335 in Adults With Chronic Spontaneous Urticaria (CSU)", "sponsor": "Calixis Inc.", "phase": "PHASE2", "start": "2026-09-15", "cities": [ "Smyrna" ] }, { "id": "NCT07711002", "title": "Saruparib in Combination With Physician's Choice of ARPI in Patients With mHSPC Previously Treated With Docetaxel or 177Lu-PSMA Therapy Without Disease Progress", "sponsor": "AstraZeneca", "phase": "PHASE3", "start": "2026-09-15", "cities": [ "Nashville" ] }, { "id": "NCT07531498", "title": "Muscle Aging Phenotypes in Childhood Cancer Survivors", "sponsor": "St. Jude Children's Research Hospital", "phase": "OBSERVATIONAL", "start": "2026-09-14", "cities": [ "Memphis" ] }, { "id": "NCT07606365", "title": "A Study in Adults With Geographic Atrophy", "sponsor": "Sitala Bio LTD", "phase": "PHASE2", "start": "2026-09-11", "cities": [ "Nashville" ] }, { "id": "NCT07815665", "title": "A Study of Ivonescimab in Combination With Enfortumab Vedotin vs Pembrolizumab in Combination With Enfortumab Vedotin in Metastatic Urothelial Carcinoma", "sponsor": "Summit Therapeutics", "phase": "PHASE2/PHASE3", "start": "2026-09-10", "cities": [ "Nashville" ] }, { "id": "NCT07813637", "title": "Phase 1 Trial to Study JANX013 and JANX007 Combination in mCRPC", "sponsor": "Janux Therapeutics", "phase": "PHASE1", "start": "2026-09-10", "cities": [ "Nashville" ] }, { "id": "NCT07788521", "title": "Comparison of ACUVUE® OASYS MAX 1-Day Multifocal and DAILIES® AquaComfort Plus® Multifocal", "sponsor": "Johnson & Johnson Vision Care, Inc.", "phase": "NA", "start": "2026-09-10", "cities": [ "Memphis" ] }, { "id": "NCT07623161", "title": "A Study to Compare Elritercept to Placebo in Adults With 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"Tricuspid Regurgitation Treatment With LAPLACE Transcatheter Tricuspid Valve Replacement System", "sponsor": "Laplace Interventional, Inc", "phase": "NA", "start": "2026-09-04", "cities": [ "Kingsport" ] }, { "id": "NCT07805707", "title": "A Study on the Efficacy of a Vaccine Against Influenza in Adults ≥65 Years of Age", "sponsor": "GlaxoSmithKline", "phase": "PHASE3", "start": "2026-09-02", "cities": [ "Knoxville" ] }, { "id": "NCT07609719", "title": "A Study of Ocrelizumab Administered Subcutaneously in Participants With Multiple Sclerosis Who Switch From an Approved Anti-CD20 Therapy", "sponsor": "Genentech, Inc.", "phase": "PHASE4", "start": "2026-09-02", "cities": [ "Cordova" ] }, { "id": "NCT07637578", "title": "A Study of Elranatamab Outpatient Administration in Patients With Relapsed/Refractory Multiple Myeloma", "sponsor": "SCRI Development Innovations, LLC", "phase": "PHASE2", "start": "2026-09-01", "cities": [ "Nashville" ] }, { "id": "NCT07624305", "title": "A Phase III 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the Knee", "sponsor": "Fin-Ceramica Faenza Spa", "phase": "NA", "start": "2026-09", "cities": [ "Jackson" ] }, { "id": "NCT07245420", "title": "Evaluation Of Cardiovascular Health Outcomes Among Survivors 2", "sponsor": "St. Jude Children's Research Hospital", "phase": "NA", "start": "2026-09", "cities": [ "Memphis" ] }, { "id": "NCT07743463", "title": "A Study of Once-daily Oral ASC30 to Evaluate the Efficacy and Safety in Adult Participants With Obesity or Overweight With Weight-Related Comorbidities", "sponsor": "Ascletis Pharma (China) Co., Limited", "phase": "PHASE3", "start": "2026-08-31", "cities": [ "Memphis" ] }, { "id": "NCT07845487", "title": "A Trial to Investigate PALI-2108 Versus Placebo in Participants With Moderately to Severely Active Ulcerative Colitis", "sponsor": "Palisade Bio", "phase": "PHASE2", "start": "2026-08-28", "cities": [ "Cordova" ] }, { "id": "NCT07743450", "title": "A Study of Once-daily Oral ASC30 to Evaluate the Efficacy and Safety in Adult Participants With Obesity or Overweight With Type 2 Diabetes", "sponsor": "Ascletis Pharma (China) Co., Limited", "phase": "PHASE3", "start": "2026-08-28", "cities": [ "Memphis" ] }, { "id": "NCT07766655", "title": "Studying NMDA and Sigma-1 in Smoking Cessation Treatment (SUMMIT)", "sponsor": "Axsome Therapeutics, Inc.", "phase": "PHASE3", "start": "2026-08-27", "cities": [ "Knoxville", "Memphis", "Nashville" ] }, { "id": "NCT07705555", "title": "A Clinical Trial of MK-8748 Compared to Aflibercept in Participants With Diabetic Macular Edema (MK-8748-004)", "sponsor": "Merck Sharp & Dohme LLC", "phase": "PHASE3", "start": "2026-08-27", "cities": [ "Johnson City", "Knoxville" ] }, { "id": "NCT07794579", "title": "A Study of Orforglipron in Participants With Overweight at Risk of Development of Obesity-Related Complications or Progression to Class 1 Obesity", "sponsor": "Eli Lilly and Company", "phase": "PHASE3", "start": "2026-08-26", "cities": [ "Knoxville", "Nashville" ] }, { "id": "NCT07771465", "title": "A Study of the Long-term Safety and Efficacy of Danicamtiv in Adults With Symptomatic Genetic and Familial Dilated Cardiomyopathy", "sponsor": "Kardigan, Inc.", "phase": "PHASE3", "start": "2026-08-26", "cities": [ "Nashville" ] }, { "id": "NCT07729462", "title": "A Study to Learn About the Study Medicine Called Rimegepant in Adults When Used for the Prevention of Chronic Migraine", "sponsor": "Pfizer", "phase": "PHASE3", "start": "2026-08-26", "cities": [ "Memphis" ] }, { "id": "NCT07797335", "title": "AMBITION 7: A Research Study Investigating How Well Zenagamtide Lowers Blood Sugar and Body Weight Compared to Insulin Glargine in People With Type 2 Diabetes a", "sponsor": "Novo Nordisk A/S", "phase": "PHASE3", "start": "2026-08-24", "cities": [ "Bristol", "Knoxville", "Nashville" ] }, { "id": "NCT07783425", "title": "A Study to Learn About the Study Medicine Called Tilrekimig in People With Moderate-to Severe Eczema", "sponsor": "Pfizer", "phase": "PHASE3", "start": "2026-08-24", "cities": [ "Memphis" ] }, { "id": "NCT07776509", "title": "A Study to Evaluate Effect of AZD6234 as an Adjunct to Incretin-based Therapies in Adult Participants With Obesity or Overweight With Weight-related Comorbidity", "sponsor": "AstraZeneca", "phase": "PHASE3", "start": "2026-08-24", "cities": [ "Franklin" ] }, { "id": "NCT07754461", "title": "A Study to Test Whether Survodutide Helps People With Type 2 Diabetes Control Their Blood Sugar", "sponsor": "Boehringer Ingelheim", "phase": "PHASE3", "start": "2026-08-24", "cities": [ "Chattanooga", "Memphis" ] }, { "id": "NCT07737743", "title": "A Phase 2a/b Study to Assess the Efficacy, Safety and Tolerability of DDY391 in Participants With Sjögren's Disease", "sponsor": "Novartis Pharmaceuticals", "phase": "PHASE2", "start": "2026-08-24", "cities": [ "Memphis" ] }, { "id": "NCT07783542", "title": "ORKA-002 Versus Placebo in Participants With Moderate-to-Severe Hidradenitis Suppurativa", "sponsor": "Oruka Therapeutics, Inc.", "phase": "PHASE2", "start": "2026-08-21", "cities": [ "Smyrna" ] }, { "id": "NCT07753993", "title": "A Study to Investigate Outcomes With Elecoglipron Compared With Placebo in Adult Participants With Chronic Kidney Disease.", "sponsor": "AstraZeneca", "phase": "PHASE3", "start": "2026-08-21", "cities": [ "Knoxville", "Morristown" ] }, { "id": "NCT07428993", "title": "Evaluating Efficacy of B7-H3-CAR T Cells Administered at the End of Upfront Map Chemotherapy in Patients With Newly Diagnosed High-Risk Osteosarcoma", "sponsor": "St. Jude Children's Research Hospital", "phase": "PHASE2", "start": "2026-08-21", "cities": [ "Memphis" ] }, { "id": "NCT07784270", "title": "A Study to Evaluate Effect of AZD6234 in Adult Participants With Type 2 Diabetes Mellitus and Obesity or Overweight", "sponsor": "AstraZeneca", "phase": "PHASE3", "start": "2026-08-20", "cities": [ "Franklin", "Jackson", "Knoxville" ] }, { "id": "NCT07772921", "title": "A Study to Learn About the Study Medicine Called Tilrekimig in People With Severe Asthma", "sponsor": "Pfizer", "phase": "PHASE3", "start": "2026-08-20", "cities": [ "Smyrna" ] }, { "id": "NCT07514819", "title": "Integration of Adaptive Proton Therapy in Pediatric Solid Tumors and Hodgkin's Lymphoma", "sponsor": "St. Jude Children's Research Hospital", "phase": "NA", "start": "2026-08-20", "cities": [ "Memphis" ] }, { "id": "NCT07279467", "title": "Study of Oral Food Challenge Biomarkers (SAFER)", "sponsor": "National Institute of Allergy and Infectious Diseases (NIAID)", "phase": "OBSERVATIONAL", "start": "2026-08-20", "cities": [ "Nashville" ] }, { "id": "NCT07784725", "title": "A Study to Evaluate Effect of AZD6234 in Adult Participants With Obesity or Overweight With Weight-related Comorbidity Without Type 2 Diabetes Mellitus", "sponsor": "AstraZeneca", "phase": "PHASE3", "start": "2026-08-19", "cities": [ "Kingsport", "Memphis" ] }, { "id": "NCT07745361", "title": "Study of Oral MRT-2359 With Apalutamide in Prostate Cancer", "sponsor": "Monte Rosa Therapeutics, Inc", "phase": "PHASE2", "start": "2026-08-18", "cities": [ "Nashville" ] }, { "id": "NCT07022678", "title": "Xylitol Dental Wipes for the Reduction of Bloodstream Infection Risk in Children With Acute Myeloid Leukemia", "sponsor": "Children's Oncology Group", "phase": "PHASE3", "start": "2026-08-14", "cities": [ "Knoxville", "Nashville" ] }, { "id": "NCT07774455", "title": "Pacritinib Effectiveness in Real-world Settings", "sponsor": "Swedish Orphan Biovitrum", "phase": "OBSERVATIONAL", "start": "2026-08-13", "cities": [ "Nashville" ] }, { "id": "NCT07619131", "title": "A Phase III Study to Assess the Effect of FDC Laroprovstat/Rosuvastatin Compared With Laroprovstat, Rosuvastatin and Placebo on LDL-C in LLT-naïve Patients.", "sponsor": "AstraZeneca", "phase": "PHASE3", "start": "2026-08-12", "cities": [ "Knoxville" ] }, { "id": "NCT07837973", "title": "Study to Assess the Effect and Safety of ALV-100 on Maintenance of Weight Loss", "sponsor": "Alveus Therapeutics, Inc.", "phase": "PHASE2", "start": "2026-08-10", "cities": [ "Nashville" ] }, { "id": "NCT07626411", "title": "Stroke and Systemic Embolism Prevention in Adult Participants With Atrial Fibrillation", "sponsor": "Regeneron Pharmaceuticals", "phase": "PHASE3", "start": "2026-08-10", "cities": [ "Tullahoma" ] }, { "id": "NCT07391774", "title": "Testing Whether Hormone Therapy With Ribociclib is as Effective as Chemotherapy Followed by Hormone Therapy With Ribociclib for the Treatment of High Anatomic S", "sponsor": "National Cancer Institute (NCI)", "phase": "PHASE3", "start": "2026-08-10", "cities": [ "Collierville", "Memphis" ] }, { "id": "NCT07767903", "title": "A Trial of the Efficacy and Safety of a Fixed Dose of SEP-363856 in Adults With Generalized Anxiety Disorder", "sponsor": "Otsuka Pharmaceutical Development & Commercialization, Inc.", "phase": "PHASE3", "start": "2026-08-06", "cities": [ "Memphis" ] }, { "id": "NCT07498335", "title": "Study to Assess the Efficacy, Pharmacokinetics, Safety and Tolerability of Atrasentan in Pediatric Patients With Primary IgAN", "sponsor": "Novartis Pharmaceuticals", "phase": "PHASE3", "start": "2026-08-06", "cities": [ "Memphis" ] }, { "id": "NCT07752979", "title": "Safety and Efficacy of ABBV-295 in Adults With Obesity or Overweight With Weight-Related Comorbidities", "sponsor": "AbbVie", "phase": "PHASE2", "start": "2026-08-04", "cities": [ "Bristol", "Knoxville", "Nashville" ] }, { "id": "NCT07282613", "title": "A Research Study to See How Much CagriSema Lowers Blood Sugar and Body Weight Compared to Placebo in Children and Adolescents With Type 2 Diabetes", "sponsor": "Novo Nordisk A/S", "phase": "PHASE3", "start": "2026-08-04", "cities": [ "Memphis" ] }, { "id": "NCT07231380", "title": "A Comparison of Cyclic Manual Direct Aspiration Thrombectomy (Plunger Technique) vs. Static Manual Direct Aspiration Thrombectomy for Treatment of Acute Large V", "sponsor": "Vanderbilt University Medical Center", "phase": "NA", "start": "2026-08-04", "cities": [ "Nashville" ] }, { "id": "NCT07779408", "title": "Study to Assess Safety and Immunogenicity of an Egg-based H5N8 Influenza Vaccine at Multiple Dose Levels Adjuvanted With Matrix-M in Healthy Participants 18 Yea", "sponsor": "Sanofi", "phase": "PHASE1/PHASE2", "start": "2026-08-03", "cities": [ "Knoxville" ] }, { "id": "NCT07723248", "title": "A Study to Learn About the Investigational Drug Rinzimetostat (ORIC-944) in Patients With mCRPC Who Were Previously Treated With Abiraterone Acetate (Himalayas-", "sponsor": "ORIC Pharmaceuticals", "phase": "PHASE3", "start": "2026-08-03", "cities": [ "Nashville" ] }, { "id": "NCT07674654", "title": "A Long-Term Safety Study of Elismetrep (K-304) in the Acute Treatment of Migraine", "sponsor": "TriGemX Bio, Inc.", "phase": "PHASE3", "start": "2026-08-03", "cities": [ "Chattanooga", "Nashville" ] }, { "id": "NCT07516093", "title": "Study of NX-5948 Versus Pirtobrutinib in 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Aisen", "phase": "PHASE2", "start": "2026-07-06", "cities": [ "Nashville" ] }, { "id": "NCT07460765", "title": "Safety and Feasibility of Nivolumab-IRDye800CW in Patients With Head and Neck Squamous Cell Carcinoma (HNSCC)", "sponsor": "Vanderbilt-Ingram Cancer Center", "phase": "PHASE1", "start": "2026-07-03", "cities": [ "Nashville" ] }, { "id": "NCT07499258", "title": "Axonics R20 Post-Market Clinical Follow-up (PMCF) Study for the Indication of Fecal Incontinence", "sponsor": "Axonics, Inc.", "phase": "OBSERVATIONAL", "start": "2026-07-02", "cities": [ "Nashville" ] }, { "id": "NCT07365241", "title": "A Study to Evaluate Adverse Events and Change in Disease Activity of Intravenous ABBV-706 Versus Standard of Care in Adult Participants With Relapsed/Refractory", "sponsor": "AbbVie", "phase": "PHASE3", "start": "2026-07-02", "cities": [ "Knoxville", "Memphis", "Nashville" ] }, { "id": "NCT07719361", "title": "A Study in Patients With Metastatic Castration-Resistant Prostate Cancer", "sponsor": "Flare Therapeutics Inc.", "phase": "PHASE1", "start": "2026-07-01", "cities": [ "Nashville" ] }, { "id": "NCT07710300", "title": "Randomized Controlled Trial Testing a Training Program About Section 504 of the Rehabilitation Act", "sponsor": "Vanderbilt University", "phase": "NA", "start": "2026-07-01", "cities": [ "Nashville" ] }, { "id": "NCT07645924", "title": "A Study to Evaluate the Efficacy and Safety of Elismetrep (K-304) in the Acute Treatment of Migraine", "sponsor": "TriGemX Bio, Inc.", "phase": "PHASE3", "start": "2026-07-01", "cities": [ "Chattanooga", "Nashville" ] }, { "id": "NCT07609108", "title": "Pridopidine Phase 3 Study in Huntington's Disease", "sponsor": "Prilenia", "phase": "PHASE3", "start": "2026-07-01", "cities": [ "Nashville" ] }, { "id": "NCT07559903", "title": "ANDREAS Registry (Assessment of Novel Drug-coated Balloon Revascularization: Effectiveness, Angiographic Outcomes, and Safety)", "sponsor": "Emory University", "phase": "OBSERVATIONAL", "start": "2026-07-01", "cities": [ "Nashville" ] }, { "id": "NCT07426757", "title": "An Open-Label Study to Evaluate PF-07994525 in Participants With Advanced Cancers", "sponsor": "Pfizer", "phase": "PHASE1", "start": "2026-07-01", "cities": [ "Nashville" ] }, { "id": "NCT07172971", "title": "Sodium/Glucose Cotransporter-2 Inhibitors (SGLT2i) Therapy in Duchenne Cardiomyopathy", "sponsor": "Vanderbilt University Medical Center", "phase": "PHASE1", "start": "2026-07-01", "cities": [ "Nashville" ] }, { "id": "NCT07095894", "title": "A RCT of Spectacles With Aspherical Lenslets or 0.05% Atropine for Myopia Control", "sponsor": "Jaeb Center for Health Research", "phase": "PHASE3", "start": "2026-07-01", "cities": [ "Nashville" ] }, { "id": "NCT07751042", "title": "Phase 1/2 Study of Intravenous Injection of STX-003 in Advanced Solid Tumors as Monotherapy or in Combination With Pembrolizumab", "sponsor": "Strand Therapeutics Inc.", "phase": "PHASE1/PHASE2", "start": "2026-06-30", "cities": [ "Nashville" ] }, { "id": "NCT07747103", "title": "An Open-Label, Single-Arm Study to Investigate the Efficacy and Safety of North Star Desiccated Porcine Thyroid Extract Tablets.", "sponsor": "Neuvosyn Laboratories, LLC", "phase": "PHASE3", "start": "2026-06-30", "cities": [ "Chattanooga" ] }, { "id": "NCT07614984", "title": "A Clinical Trial of MK-7262 and Enlicitide in Participants With High Lipoprotein(a) (MK-7262-004)", "sponsor": "Merck Sharp & Dohme LLC", "phase": "PHASE2", "start": "2026-06-30", "cities": [ "Kingsport" ] }, { "id": "NCT07589634", "title": "A Study Evaluating the Prophylactic Use of Tocilizumab to Prevent Cytokine Release Syndrome With Ramantamig Administration in Participants With Relapsed/Refract", "sponsor": "Janssen Research & Development, LLC", "phase": "PHASE2", "start": "2026-06-30", "cities": [ "Nashville" ] }, { "id": "NCT07489066", "title": "Symbiotic-Lung-10: A Study to Learn About PF-08634404 Alone or in Combination in Early-stage or Locally 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Therapeutics Ltd.", "phase": "PHASE3", "start": "2026-06-26", "cities": [ "Chattanooga", "Memphis" ] }, { "id": "NCT07284602", "title": "Trial to Evaluate the Efficacy and Safety of LYT-100 (Deupirfenidone) Compared to Pirfenidone in Adults With Idiopathic Pulmonary Fibrosis (IPF)", "sponsor": "PureTech", "phase": "PHASE3", "start": "2026-06-26", "cities": [ "Franklin", "Knoxville" ] }, { "id": "NCT07717892", "title": "Forward Treatment of Attention Deficit and Hyperactivity Using Solriamfetol (FOCUS-3)", "sponsor": "Axsome Therapeutics, Inc.", "phase": "PHASE3", "start": "2026-06-25", "cities": [ "Memphis" ] }, { "id": "NCT07621237", "title": "A Study to Evaluate TNX-102 SL Monotherapy Versus Placebo in Participants With Major Depressive Disorder (MDD)", "sponsor": "Tonix Pharmaceuticals, Inc.", "phase": "PHASE2", "start": "2026-06-25", "cities": [ "Mephis" ] }, { "id": "NCT07357597", "title": "An Open-label, Single-arm Study of Prophylaxis for Datopotamab Deruxtecan (Dato-DXd) -Related Stomatitis in Eligible Patients With Metastatic or Inoperable Loca", "sponsor": "AstraZeneca", "phase": "PHASE4", "start": "2026-06-24", "cities": [ "Knoxville" ] }, { "id": "NCT07224672", "title": "A Study to Evaluate the Efficacy and Safety of Belantamab Mafodotin in Combination With Cyclophosphamide, Bortezomib, and Dexamethasone in Adult Participants Wi", "sponsor": "GlaxoSmithKline", "phase": "PHASE2", "start": "2026-06-24", "cities": [ "Nashville" ] }, { "id": "NCT07694440", "title": "A Study of MZE782 in Adults With PKU", "sponsor": "Maze Therapeutics", "phase": "PHASE2", "start": "2026-06-23", "cities": [ "Memphis" ] }, { "id": "NCT07673107", "title": "Study of AGN-151607-DP to Assess Adverse Events and Change in Disease Activity in Adult Participants With Upper Limb Essential Tremor", "sponsor": "AbbVie", "phase": "PHASE2", "start": "2026-06-23", "cities": [ "Memphis" ] }, { "id": "NCT07605429", "title": "BEACON - Phase III Clinical Study of Rugonersen in Angelman 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"start": "2026-05-14", "cities": [ "Nashville" ] }, { "id": "NCT07387549", "title": "A Study to Assess How Well and Safely Elafibranor Works in Adult Participants With Primary Sclerosing Cholangitis", "sponsor": "Ipsen", "phase": "PHASE3", "start": "2026-05-14", "cities": [ "Cordova", "Johnson City" ] }, { "id": "NCT07277946", "title": "AtraUmatic Laparoscopic HerNia Repair Clinical Investigation to Evaluate the Safety and Performance of The ECLIPSIUM System for Mesh Fixation IDE", "sponsor": "Tissium", "phase": "NA", "start": "2026-05-14", "cities": [ "Knoxville" ] }, { "id": "NCT07142252", "title": "Rezpegaldesleukin (NKTR-358) in New Onset Type 1 Diabetes Mellitus", "sponsor": "National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)", "phase": "PHASE2", "start": "2026-05-14", "cities": [ "Nashville" ] }, { "id": "NCT07764133", "title": "Whole Body Metabolic Activity as a Reflection of Tumor Metabolic Dysregulation and a Predictor of Treatment Response in Ovarian 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"id": "NCT06930755", "title": "Study of NMS-03305293 in Adult Patients With Relapsed Ovarian Cancer", "sponsor": "Nerviano Medical Sciences", "phase": "PHASE1", "start": "2026-05-13", "cities": [ "Nashville" ] }, { "id": "NCT06465199", "title": "Eflornithine (DFMO) and AMXT 1501 for Neuroblastoma, CNS Tumors, and Sarcomas", "sponsor": "Milton S. 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People With Muscle Invasive Bladder Cancer (EV-309)", "sponsor": "Astellas Pharma Global Development, Inc.", "phase": "PHASE3", "start": "2026-05-11", "cities": [ "Nashville" ] }, { "id": "NCT07539311", "title": "Study to Assess the Efficacy and Safety of Rina-S in Participants With Advanced Gastrointestinal (GI) Cancers", "sponsor": "Genmab", "phase": "PHASE2", "start": "2026-05-11", "cities": [ "Nashville" ] }, { "id": "NCT07441694", "title": "Study of INCA036978 in Participants With Myeloproliferative Neoplasms", "sponsor": "Incyte Corporation", "phase": "PHASE1", "start": "2026-05-11", "cities": [ "Nashville" ] }, { "id": "NCT07436728", "title": "A Study of TAK-505 in Adults With Solid Tumors", "sponsor": "Takeda", "phase": "PHASE1/PHASE2", "start": "2026-05-11", "cities": [ "Nashville" ] }, { "id": "NCT07214532", "title": "Signatera-Guided CDK4/6 Inhibitor Therapy in Breast Cancer", "sponsor": "Natera, Inc.", "phase": "NA", "start": "2026-05-08", "cities": [ "Germantown", "Nashville" ] }, { "id": "NCT07610837", "title": "Study of AZD2389 Safety, Tolerability, and Pharmacodynamics in Adults With Steatotic Liver Disease and Advanced Fibrosis", "sponsor": "AstraZeneca", "phase": "PHASE2", "start": "2026-05-07", "cities": [ "Clarksville" ] }, { "id": "NCT07543120", "title": "An Open-label Extension Safety and Efficacy Study of QCZ484 in Hypertensive Patients.", "sponsor": "Novartis Pharmaceuticals", "phase": "PHASE2", "start": "2026-05-07", "cities": [ "Memphis" ] }, { "id": "NCT07549412", "title": "A Study of Precemtabart Tocentecan With or Without Bevacizumab Compared to Trifluridine/Tipiracil Plus Bevacizumab in Participants With Previously Treated Metas", "sponsor": "EMD Serono Research & Development Institute, Inc.", "phase": "PHASE3", "start": "2026-05-06", "cities": [ "Nashville" ] }, { "id": "NCT07427394", "title": "Study to Evaluate the Safety and Tolerability of Camizestrant in Combination With Atirmociclib in Women With Advanced Breast Cancer", "sponsor": "AstraZeneca", "phase": "PHASE2", "start": "2026-05-06", "cities": [ "Nashville" ] }, { "id": "NCT07415031", "title": "A Solid Tumor Study for Long Term Treatment of Cancer Patients Who Participated in Adagrasib Studies", "sponsor": "Mirati Therapeutics Inc.", "phase": "PHASE2", "start": "2026-05-06", "cities": [ "Germantown" ] }, { "id": "NCT07568834", "title": "Impact of Pelvic Pain Podcast", "sponsor": "Vanderbilt University Medical Center", "phase": "NA", "start": "2026-05-05", "cities": [ "Nashville" ] }, { "id": "NCT07226453", "title": "Target Validation and Efficacy of Metformin in Patients With Posterior Fossa Group A (PFA) Ependymoma", "sponsor": "University of California, San Francisco", "phase": "PHASE2", "start": "2026-05-05", "cities": [ "Memphis" ] }, { "id": "NCT07611110", "title": "AZD2265 Compared With Standard of Care in PSMA-positive Metastatic Castration-resistant Prostate Cancer (VECTRA-01)", "sponsor": "AstraZeneca", "phase": "PHASE3", "start": 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"start": "2026-04-07", "cities": [ "Nashville" ] }, { "id": "NCT07424404", "title": "A Study to Evaluate the Long-term Safety and Tolerability of Xanomeline and Trospium Chloride for the Treatment of Psychiatric Disorders in Children and Adolesc", "sponsor": "Karuna Therapeutics, Inc., a Bristol Myers Squibb company", "phase": "PHASE3", "start": "2026-04-07", "cities": [ "Nashville" ] }, { "id": "NCT07430956", "title": "Stroke and Systemic Embolism Prevention in Adult Participants With Atrial Fibrillation for Whom Oral Anticoagulation is Unsuitable", "sponsor": "Regeneron Pharmaceuticals", "phase": "PHASE3", "start": "2026-04-03", "cities": [ "Tullahoma" ] }, { "id": "NCT07540221", "title": "A Study to Evaluate the Pharmacokinetics and Safety of XEMBIFY Versus Gamunex-C in Participants With Chronic Inflammatory Demyelinating Polyradiculoneuropathy", "sponsor": "Grifols Therapeutics LLC", "phase": "PHASE3", "start": "2026-04-02", "cities": [ "Cordova" ] }, { "id": "NCT07456696", 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"sponsor": "Southern College of Optometry", "phase": "NA", "start": "2026-04", "cities": [ "Memphis" ] }, { "id": "NCT07551661", "title": "Effects of an Independent Walking Program With Walking Poles in People With Parkinson Disease", "sponsor": "East Tennessee State University", "phase": "NA", "start": "2026-04", "cities": [ "Johnson City" ] }, { "id": "NCT07462377", "title": "A Phase 1 Study of EPI-326 in EGFR-mutant NSCLC and HNSCC", "sponsor": "EpiBiologics", "phase": "PHASE1", "start": "2026-03-31", "cities": [ "Nashville" ] }, { "id": "NCT07439653", "title": "A Study of TORL-5-700 in Relapsed/Refractory Non Hodgkin's Lymphoma", "sponsor": "TORL Biotherapeutics, LLC", "phase": "PHASE1/PHASE2", "start": "2026-03-31", "cities": [ "Nashville" ] }, { "id": "NCT07191119", "title": "Transcutaneous Auricular Vagus Nerve Stimulation for Insomnia in Survivors of Childhood Acute Lymphoblastic Leukemia", "sponsor": "St. Jude Children's Research Hospital", "phase": "NA", "start": 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"cities": [ "Memphis" ] }, { "id": "NCT07116616", "title": "A Study of mRNA-2808 in Participants With Relapsed or Refractory Multiple Myeloma", "sponsor": "ModernaTX, Inc.", "phase": "PHASE1/PHASE2", "start": "2025-09-30", "cities": [ "Nashville" ] }, { "id": "NCT07106762", "title": "Phase 2/3 Trial of Izalontamab Brengitecan vs Platinum-based Chemotherapy for Metastatic Urothelial Cancer With Disease Progression on or After Immunotherapy", "sponsor": "Bristol-Myers Squibb", "phase": "PHASE2/PHASE3", "start": "2025-09-30", "cities": [ "Nashville" ] }, { "id": "NCT07204340", "title": "TLN-372 in Advanced KRAS Mutant Solid Tumors", "sponsor": "Treeline Biosciences, Inc.", "phase": "PHASE1", "start": "2025-09-29", "cities": [ "Nashville" ] }, { "id": "NCT07144280", "title": "A Study to Learn About the Study Medicine Called PF-08046054/SGN-PDL1V Versus Docetaxel in Adult Participants With Previously-Treated Programmed Cell Death Liga", "sponsor": "Pfizer", "phase": "PHASE3", "start": "2025-09-29", "cities": [ "Bartlett", "Chattanooga", "Cleveland", "Collierville" ] }, { "id": "NCT07011576", "title": "A Study of Fruquintinib Plus FOLFIRI as Second-Line Treatment for Participants With Metastatic Colorectal Cancer (FRUITFUL)", "sponsor": "SCRI Development Innovations, LLC", "phase": "PHASE2", "start": "2025-09-29", "cities": [ "Nashville" ] }, { "id": "NCT07028853", "title": "This Study Will Explore Whether a Combination of the Investigational Drug Mevrometostat (PF-06821497) and Enzalutamide Will Work Better Than Taking Enzalutamide", "sponsor": "Pfizer", "phase": "PHASE3", "start": "2025-09-28", "cities": [ "Chattanooga", "Cleveland", "Cookeville", "Dickson" ] }, { "id": "NCT07133633", "title": "A Clinical Study of Tulisokibart (MK-7240) to Treat Radiographic Axial Spondyloarthritis (MK-7240-013)", "sponsor": "Merck Sharp & Dohme LLC", "phase": "PHASE2", "start": "2025-09-26", "cities": [ "Murfreesboro" ] }, { "id": "NCT07129993", "title": "Study of Datopotamab 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Henderson", "phase": "OBSERVATIONAL", "start": "2025-09-26", "cities": [ "Nashville" ] }, { "id": "NCT07159763", "title": "A Study to Evaluate the Safety and Efficacy of MK-1406/CD388 for Prevention of Influenza (MK-1406-005/CD388.SQ.3.06)", "sponsor": "Cidara Therapeutics Inc., a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA)", "phase": "PHASE3", "start": "2025-09-25", "cities": [ "Hendersonville" ] }, { "id": "NCT07052370", "title": "TCRαβ-depleted Progenitor Cell Graft With Early Memory T-cell DLI, Plus Selected Use of Blinatumomab, in naïve T-cell Depleted Haploidentical Donor Hematopoieti", "sponsor": "St. Jude Children's Research Hospital", "phase": "PHASE1", "start": "2025-09-25", "cities": [ "Memphis" ] } ], "fetched_at": "2026-11-04T18:42:18Z" }